Lower urinary tract symptoms (LUTS) are highly prevalent, cause bother and impair quality of life (QoL). LUTS can be divided into storage, voiding and post-micturition symptoms and are often perceived as a normal process of ageing. An increasing awareness of LUTS is warranted to discuss management options that could increase QoL. These include conservative, medical and surgical treatment. In the upcoming webinar, we discuss mono- and combination medical treatment options for male LUTS. We aim to provide different clinical scenarios which should help to understand current pharmacological treatment options according to the EAU guidelines for non-neurogenic male LUTS.